BMP pathway regulation of and by macrophages.

BMP pathway regulation of and by macrophages.

Pulmonary arterial hypertension (PAH) is a disease of progressively increasing pulmonary vascular resistance, associated with mutations of the type 2 receptor for the BMP pathway, BMPR2. The canonical signaling pathway for BMPR2 is through the SMAD family of transcription factors. BMPR2 is expressed...

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Bibliographic Details
Main Authors: Megha Talati, James West, Rinat Zaynagetdinov, Charles C Hong, Wei Han, Tom Blackwell, Linda Robinson, Timothy S Blackwell, Kirk Lane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979749?pdf=render

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http://europepmc.org/articles/PMC3979749?pdf=render

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