Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis

Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis

Abstract Objective Our aim was to identify natural products with anti-tubercular activity. Results A set of ~ 500 purified natural product compounds was screened for inhibition against the human pathogen Mycobacterium tuberculosis. A series of cyclic hexapeptides with anti-tubercular activity was id...

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Bibliographic Details
Main Authors: Sheo B. Singh, Joshua Odingo, Mai A. Bailey, Bjorn Sunde, Aaron Korkegian, Theresa O’Malley, Yulia Ovechkina, Thomas R. Ioerger, James C. Sacchettini, Katherine Young, David B. Olsen, Tanya Parish
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Research Notes
Subjects:
Mycobacteria
Antibacterial
Natural product
Anti-tubercular
Antibiotic resistance
Online Access:http://link.springer.com/article/10.1186/s13104-018-3526-z

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