Pioglitazone Attenuates Vascular Fibrosis in Spontaneously Hypertensive Rats
Objective. We sought to investigate whether the peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand pioglitazone can attenuate vascular fibrosis in spontaneously hypertensive rats (SHRs) and explore the possible molecular mechanisms. Methods. SHRs (8-week-old males) were randomly divided in...
Main Authors: | Dengfeng Gao, Ning Ning, Guanghua Hao, Xiaolin Niu |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2012/856426 |
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