Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia

Abstract Recent genome-wide association studies (GWAS) have identified multiple loci associated with coronary artery disease (CAD) among predominantly Europeans. However, their relevance to multi-ethnic populations from Southeast Asia is largely unknown. We performed a meta-analysis of four GWAS com...

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Bibliographic Details
Main Authors: Yi Han, Rajkumar Dorajoo, Xuling Chang, Ling Wang, Chiea-Chuen Khor, Xueling Sim, Ching-Yu Cheng, Yuan Shi, Yih Chung Tham, Wanting Zhao, Miao Ling Chee, Charumathi Sabanayagam, Miao Li Chee, Nicholas Tan, Tien Yin Wong, E-Shyong Tai, Jianjun Liu, Daniel Y. T. Goh, Jian-Min Yuan, Woon-Puay Koh, Rob M. van Dam, Adrian F. Low, Mark Yan-Yee Chan, Yechiel Friedlander, Chew-Kiat Heng
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-18214-z