Infantile nodular fasciitis of the hand: A case report and literature review

Pediatric nodular fasciitis is uncommon and has a preference for the head and neck region. Occurrence in other anatomic locations is uncommon. We describe here a case of nodular fasciitis that arose in the hand of a newborn infant who presented with a rapidly growing mass. On MRI, it was heterogeneo...

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Bibliographic Details
Main Authors: I Weng Lao, Xiaohang Liu, Lin Yu, Jian Wang
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Human Pathology: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214330016300013
Description
Summary:Pediatric nodular fasciitis is uncommon and has a preference for the head and neck region. Occurrence in other anatomic locations is uncommon. We describe here a case of nodular fasciitis that arose in the hand of a newborn infant who presented with a rapidly growing mass. On MRI, it was heterogeneous isointense on T1-weighted and hyperintense on T2-weighted images. Histological examination showed short intersecting fascicles of uniform spindled myofibroblasts embedded in a myxoid to collagenous stroma, consistent with a nodular fasciitis. However, the lesion was initially diagnosed as an infantile fibrosarcoma due to the rapid growth, brisk mitotic activity and focally infiltrative architecture. This study illustrates that unusual presentation of nodular fasciitis may cause diagnostic confusion.
ISSN:2214-3300