Preoperative Ultrasound Guided Fine Needle Aspiration Cytology of Ovarian Lesions- Is It a Rapid and Effective Diagnostic Modality?

• Main Authors: Soumit Dey, Saikat Datta, Snehamay Chaudhuri, Prabir Chandra Paul, Binny Khandakar, Sonali Mandal
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2016-03-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: diagnostic accuracy; ovarian cancer; ovarian tumour
• Online Access: https://jcdr.net/articles/PDF/7447/15729_CE(RA1)_F(T)_PF1(Vsu_Om)_PFA(AK)_PF2(PAG).pdf
• ISSN: 2249-782X; 0973-709X

Introduction: The deep seated ovarian lesions unapproachable by unguided aspiration cytology were easily done under ultrasound guidance. It gave a before hand cytological diagnosis of the lesion to the surgeon determining the modality of treatment for the patient. Aim: To find the diagnostic accuracy of the method of ultrasound guided cytological assessment of ovarian lesion. Materials and Methods: The study was conducted as a prospective observational study over a period of one year, in hospital setting, where ultrasound guided fine needle aspiration had been used to aspirate ovarian lesions, giving a rapid cytological diagnosis. In 43 sample cases, aspiration of fluid done from ovarian lesions were followed by cyto-centrifugation and staining by May-Grunwald-Giemsa (MGG) and Papanicolaou (Pap) stain providing a cytological opinion regarding benign/malignant nature of the lesion and further categorization. Later the cytological diagnosis was compared with final histopathological diagnosis, taking it as a gold standard. Results: The overall sensitivity, specificity, and diagnostic accuracy of ultrasound guided aspiration and cytological analysis were high, 96%, 76.92% and 89.47% respectively as calculated by comparing the cytological diagnosis with histological diagnosis, taking it as gold standard. Conclusion: This method has evolved as a highly sensitive, rapid, simple and effective modality for screening and as well as accurate preoperative diagnosis of ovarian lesions.