The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2
<p>An important contribution in the development of diabetes mellitus (DM) complications makes not only the chronic hyperglycemia but also the intense diurnal glycemia variability (GV). The aim of research was to assess systolic and diastolic heart functions in patients with chronic heart failu...
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doaj-086d59ef6a84424b9f5b57394f5332b82020-11-24T21:47:27ZengPC Technology CenterScienceRise2313-62862313-84162016-01-0113 (18)535710.15587/2313-8416.2016.5932956077The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2Виктор Денисович Сиволап0Наталья Игоревна Капшитарь1Zaporozhye state medical university 26 Mayakovsky ave., Zaporozhye, Ukraine, 69035Zaporozhye state medical university 26 Mayakovsky ave., Zaporozhye, Ukraine, 69035<p>An important contribution in the development of diabetes mellitus (DM) complications makes not only the chronic hyperglycemia but also the intense diurnal glycemia variability (GV). The aim of research was to assess systolic and diastolic heart functions in patients with chronic heart failure (CHF) of ischemic genesis on the background of DM type 2 depending on GV profile and the mean level of glycemia during the last 3 month.</p><p><strong>Methods:</strong> There were examined 65 patients who were divided into groups twice on the different categoric indicators. The first indicator – an intensity of glycemia profile (GP) variability, the second – the mean calculated level of glucose concentration in patients during the last 3 month. All patients underwent dopplerechocardiography, the standard declination and the coefficient of GP variations were calculated. An assessment of reliability of the results of statistic study was carried out by nonparametric method.</p><p><strong>Results: </strong>in patients with the high GP variability was detected the reliably greater size of the left atrium, decrease of the left ventricle output fraction, tendency to the transition of diastolic dysfunction from the I type to the II one comparing with the group with low GP variability. There was not revealed any reliable difference between groups or correlative connection of the mean level of glycemia with parameters that characterize contractility and diastolic myocardium function.</p><p><strong>Conclusions</strong><strong>:</strong> There was revealed the negative influence of the high glycemia variability on systolic and diastolic heart functions, left atrium size and there was not revealed any reliable influence of the mean level of glycemia on cardiohemodynamics</p>http://journals.uran.ua/sciencerise/article/view/59329chronic heart failurediabetes mellitussystolic and diastolic heart functionsglycemia profile variability |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Виктор Денисович Сиволап Наталья Игоревна Капшитарь |
spellingShingle |
Виктор Денисович Сиволап Наталья Игоревна Капшитарь The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 ScienceRise chronic heart failure diabetes mellitus systolic and diastolic heart functions glycemia profile variability |
author_facet |
Виктор Денисович Сиволап Наталья Игоревна Капшитарь |
author_sort |
Виктор Денисович Сиволап |
title |
The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
title_short |
The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
title_full |
The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
title_fullStr |
The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
title_full_unstemmed |
The relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
title_sort |
relationship of diurnal variability and level of glycemia with structural and functional parameters of heart in patients with chronic heart failure and diabetes mellitus type 2 |
publisher |
PC Technology Center |
series |
ScienceRise |
issn |
2313-6286 2313-8416 |
publishDate |
2016-01-01 |
description |
<p>An important contribution in the development of diabetes mellitus (DM) complications makes not only the chronic hyperglycemia but also the intense diurnal glycemia variability (GV). The aim of research was to assess systolic and diastolic heart functions in patients with chronic heart failure (CHF) of ischemic genesis on the background of DM type 2 depending on GV profile and the mean level of glycemia during the last 3 month.</p><p><strong>Methods:</strong> There were examined 65 patients who were divided into groups twice on the different categoric indicators. The first indicator – an intensity of glycemia profile (GP) variability, the second – the mean calculated level of glucose concentration in patients during the last 3 month. All patients underwent dopplerechocardiography, the standard declination and the coefficient of GP variations were calculated. An assessment of reliability of the results of statistic study was carried out by nonparametric method.</p><p><strong>Results: </strong>in patients with the high GP variability was detected the reliably greater size of the left atrium, decrease of the left ventricle output fraction, tendency to the transition of diastolic dysfunction from the I type to the II one comparing with the group with low GP variability. There was not revealed any reliable difference between groups or correlative connection of the mean level of glycemia with parameters that characterize contractility and diastolic myocardium function.</p><p><strong>Conclusions</strong><strong>:</strong> There was revealed the negative influence of the high glycemia variability on systolic and diastolic heart functions, left atrium size and there was not revealed any reliable influence of the mean level of glycemia on cardiohemodynamics</p> |
topic |
chronic heart failure diabetes mellitus systolic and diastolic heart functions glycemia profile variability |
url |
http://journals.uran.ua/sciencerise/article/view/59329 |
work_keys_str_mv |
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