Maslinic Acid, a Natural Phytoalexin-Type Triterpene from Olives — A Promising Nutraceutical?

• Main Authors: Glòria Lozano-Mena, Marta Sánchez-González, M. Emília Juan, Joana M. Planas
• Format: Article
• Language: English
• Published: MDPI AG 2014-08-01
• Series: Molecules
• Subjects: maslinic acid; phytochemical; phytoalexin; pentacyclic triterpene; biological effects; antitumor; antidiabetic; antioxidant; nutraceutical
• Online Access: http://www.mdpi.com/1420-3049/19/8/11538

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in the Mediterranean diet. In recent years, several studies have proved that maslinic acid exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. Experimental models used for the assessment of maslinic acid effects include established cell lines, which have been often used to elucidate the underlying mechanisms of action, and also animal models of different disorders, which have confirmed the effects of the triterpene in vivo. Overall, and supported by the lack of adverse effects in mice, the results provide evidence of the potential of maslinic acid as a nutraceutical, not only for health promotion, but also as a therapeutic adjuvant in the treatment of several disorders.