An Important Role for CD4+ T Cells in Adaptive Immunity to Toxoplasma gondii in Mice Lacking the Transcription Factor Batf3

An Important Role for CD4+ T Cells in Adaptive Immunity to Toxoplasma gondii in Mice Lacking the Transcription Factor Batf3

Toxoplasma gondii is a widespread parasite of animals that causes zoonotic infections in humans. Although healthy individuals generally control the infection with only moderate symptoms, it causes serious illness in newborns and those with compromised immune systems such as HIV-infected AIDS patient...

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Bibliographic Details
Main Authors: Roxane Tussiwand, Michael S. Behnke, Nicole M. Kretzer, Gary E. Grajales-Reyes, Theresa L. Murphy, Robert D. Schreiber, Kenneth M. Murphy, L. David Sibley
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mSphere
Subjects:
cd4 t cells
hiv-aids
chronic infection
dendritic cells
human immunodeficiency virus
opportunistic infection
toxoplasmosis
Online Access:https://doi.org/10.1128/mSphere.00634-20

Internet

https://doi.org/10.1128/mSphere.00634-20

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