Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India
Introduction: Vision loss can be a consequence of numerous disorders of eye and neural pathway conveying visual input to brain. A variety of conditions can affect visual pathway producing neurogenic vision loss. The presentation and course of vision loss depends on the site of involvement and underl...
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doaj-08986aa96bdb4abcbd5c8a2779e450cf2021-04-02T12:22:38ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552014-10-01050434034810.4103/0976-3147.139971Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern IndiaRajesh Verma0Mani Gupta1Tejendra Sukdeo Chaudhari2Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, IndiaDepartment of Neurology, King George Medical University, Lucknow, Uttar Pradesh, IndiaDepartment of Neurology, King George Medical University, Lucknow, Uttar Pradesh, IndiaIntroduction: Vision loss can be a consequence of numerous disorders of eye and neural pathway conveying visual input to brain. A variety of conditions can affect visual pathway producing neurogenic vision loss. The presentation and course of vision loss depends on the site of involvement and underlying etiology. We conducted this unprecedented study to evaluate the characteristics and outcome of various diseases of the visual pathway. Materials and Methods: In this prospective cohort study, we evaluated 64 patients with neurogenic visual impairment. Ophthalmological causes were excluded in all of them. Their presentation, ophthalmological characteristics and investigation findings were recorded. These patients were followed up till 6 months. Results: Out of 69 patients evaluated, 5 were excluded as they had ophthalmological abnormalities. The remaining 64 cases (113 eyes) were enrolled. 54 cases were due to diseases of anterior visual pathway and rest 10 had cortical vision loss. The etiologic distribution is as follows: Isolated optic neuritis- 12 (19%), multiple sclerosis- 4 (6.3%), neuromyelitis optica- 5 (7.9%), tubercular meningitis- 15 (23.8%), non-arteritic ischemic optic neuropathy, ischemic optic neuropathy complicating cavernous sinus thrombosis, cryptococcal meningitis, malignant infiltration of optic nerve, Crouzon’s syndrome, calvarial thickening and traumatic occipital gliosis- 1 (1.6%) case each, idiopathic intracranial hypertension, pituitary adenoma, acute disseminated encephalomyelitis, posterior reversible leukoencephalopathy- 3 (4.8%) cases each, cortical venous thrombosis 5 (7.9%), subacute scleroing panencephalitis- 4 (6.3%) cases. Conclusions: The diseases of anterior visual pathway were much more common than cortical vision loss. A majority of our patients had severe impairment of vision at presentation.http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.139971cortical venous thrombosisoptic neuritisvision loss |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rajesh Verma Mani Gupta Tejendra Sukdeo Chaudhari |
spellingShingle |
Rajesh Verma Mani Gupta Tejendra Sukdeo Chaudhari Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India Journal of Neurosciences in Rural Practice cortical venous thrombosis optic neuritis vision loss |
author_facet |
Rajesh Verma Mani Gupta Tejendra Sukdeo Chaudhari |
author_sort |
Rajesh Verma |
title |
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India |
title_short |
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India |
title_full |
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India |
title_fullStr |
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India |
title_full_unstemmed |
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India |
title_sort |
neurogenic vision loss: causes and outcome. an experience from a tertiary center in northern india |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2014-10-01 |
description |
Introduction: Vision loss can be a consequence of numerous disorders of eye and neural pathway conveying visual input to brain. A variety of conditions can affect visual pathway producing neurogenic vision loss. The presentation and course of vision loss depends on the site of involvement and underlying etiology. We conducted this unprecedented study to evaluate the characteristics and outcome of various diseases of the visual pathway. Materials and Methods: In this prospective cohort study, we evaluated 64 patients with neurogenic visual impairment. Ophthalmological causes were excluded in all of them. Their presentation, ophthalmological characteristics and investigation findings were recorded. These patients were followed up till 6 months. Results: Out of 69 patients evaluated, 5 were excluded as they had ophthalmological abnormalities. The remaining 64 cases (113 eyes) were enrolled. 54 cases were due to diseases of anterior visual pathway and rest 10 had cortical vision loss. The etiologic distribution is as follows: Isolated optic neuritis- 12 (19%), multiple sclerosis- 4 (6.3%), neuromyelitis optica- 5 (7.9%), tubercular meningitis- 15 (23.8%), non-arteritic ischemic optic neuropathy, ischemic optic neuropathy complicating cavernous sinus thrombosis, cryptococcal meningitis, malignant infiltration of optic nerve, Crouzon’s syndrome, calvarial thickening and traumatic occipital gliosis- 1 (1.6%) case each, idiopathic intracranial hypertension, pituitary adenoma, acute disseminated encephalomyelitis, posterior reversible leukoencephalopathy- 3 (4.8%) cases each, cortical venous thrombosis 5 (7.9%), subacute scleroing panencephalitis- 4 (6.3%) cases. Conclusions: The diseases of anterior visual pathway were much more common than cortical vision loss. A majority of our patients had severe impairment of vision at presentation. |
topic |
cortical venous thrombosis optic neuritis vision loss |
url |
http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.139971 |
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