Current View on the Mechanisms of Alcohol-Mediated Toxicity

Current View on the Mechanisms of Alcohol-Mediated Toxicity

Alcohol is a psychoactive substance that is widely used and, unfortunately, often abused. In addition to acute effects such as intoxication, it may cause many chronic pathological conditions. Some of the effects are very well described and explained, but there are still gaps in the explanation of em...

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Main Authors: Anna Birková, Beáta Hubková, Beáta Čižmárová, Beáta Bolerázska
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
ethanol
acetaldehyde
metabolization
oxidative stress
toxicity
Online Access:https://www.mdpi.com/1422-0067/22/18/9686
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spelling doaj-08afe2ec793c4857a094c895141e51af2021-09-26T00:22:12ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-09-01229686968610.3390/ijms22189686Current View on the Mechanisms of Alcohol-Mediated ToxicityAnna Birková0Beáta Hubková1Beáta Čižmárová2Beáta Bolerázska3Department of Medical and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, 04011 Kosice, SlovakiaDepartment of Medical and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, 04011 Kosice, SlovakiaDepartment of Medical and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, 04011 Kosice, Slovakia1st Department of Stomatology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, 04011 Kosice, SlovakiaAlcohol is a psychoactive substance that is widely used and, unfortunately, often abused. In addition to acute effects such as intoxication, it may cause many chronic pathological conditions. Some of the effects are very well described and explained, but there are still gaps in the explanation of empirically co-founded dysfunction in many alcohol-related conditions. This work focuses on reviewing actual knowledge about the toxic effects of ethanol and its degradation products.https://www.mdpi.com/1422-0067/22/18/9686ethanolacetaldehydemetabolizationoxidative stresstoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Anna Birková
Beáta Hubková
Beáta Čižmárová
Beáta Bolerázska
spellingShingle Anna Birková
Beáta Hubková
Beáta Čižmárová
Beáta Bolerázska
Current View on the Mechanisms of Alcohol-Mediated Toxicity
International Journal of Molecular Sciences
ethanol
acetaldehyde
metabolization
oxidative stress
toxicity
author_facet Anna Birková
Beáta Hubková
Beáta Čižmárová
Beáta Bolerázska
author_sort Anna Birková
title Current View on the Mechanisms of Alcohol-Mediated Toxicity
title_short Current View on the Mechanisms of Alcohol-Mediated Toxicity
title_full Current View on the Mechanisms of Alcohol-Mediated Toxicity
title_fullStr Current View on the Mechanisms of Alcohol-Mediated Toxicity
title_full_unstemmed Current View on the Mechanisms of Alcohol-Mediated Toxicity
title_sort current view on the mechanisms of alcohol-mediated toxicity
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1661-6596
1422-0067
publishDate 2021-09-01
description Alcohol is a psychoactive substance that is widely used and, unfortunately, often abused. In addition to acute effects such as intoxication, it may cause many chronic pathological conditions. Some of the effects are very well described and explained, but there are still gaps in the explanation of empirically co-founded dysfunction in many alcohol-related conditions. This work focuses on reviewing actual knowledge about the toxic effects of ethanol and its degradation products.
topic ethanol
acetaldehyde
metabolization
oxidative stress
toxicity
url https://www.mdpi.com/1422-0067/22/18/9686
work_keys_str_mv AT annabirkova currentviewonthemechanismsofalcoholmediatedtoxicity
AT beatahubkova currentviewonthemechanismsofalcoholmediatedtoxicity
AT beatacizmarova currentviewonthemechanismsofalcoholmediatedtoxicity
AT beatabolerazska currentviewonthemechanismsofalcoholmediatedtoxicity
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