Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques.
Human immunodeficiency virus (HIV) infection frequently causes neurologic disease even with anti-retroviral treatment. Although associations between MHC class I alleles and acquired immunodeficiency syndrome (AIDS) have been reported, the role MHC class I alleles play in restricting development of H...
Main Authors: | Joseph L Mankowski, Suzanne E Queen, Caroline S Fernandez, Patrick M Tarwater, Jami M Karper, Robert J Adams, Stephen J Kent |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2574413?pdf=render |
Similar Items
-
Coordinated regulation of SIV replication and immune responses in the CNS.
by: Kenneth W Witwer, et al.
Published: (2009-12-01) -
MHC and KIR polymorphisms in rhesus macaque SIV infection
by: Lutz eWalter, et al.
Published: (2015-10-01) -
Protection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV.
by: Chie Sugimoto, et al.
Published: (2010-01-01) -
Proliferation of perivascular macrophages in macaque models of lentiviral encephalitis: a potential mechanism for HIV/SIV persistence in the brain
by: W.K. Kim, et al.
Published: (2015-12-01) -
A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques.
by: Kenta Matsuda, et al.
Published: (2017-08-01)