Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs.
Cellular rejection of liver transplant allografts remains a concern despite immunosuppressant use. Existing transplant biomarkers are often not sensitive enough to detect acute or chronic rejection at an early enough stage to allow successful clinical intervention. We herein developed a cell-based s...
Main Authors: | Ling-Yee Chin, Cailah Carroll, Siavash Raigani, Danielle M Detelich, Shannon N Tessier, Gregory R Wojtkiewicz, Stephen P Schmidt, Ralph Weissleder, Heidi Yeh, Korkut Uygun, Biju Parekkadan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0225222 |
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