Challenges in proteogenomics: a comparison of analysis methods with the case study of the DREAM proteogenomics sub-challenge

Abstract Background Proteomic measurements, which closely reflect phenotypes, provide insights into gene expression regulations and mechanisms underlying altered phenotypes. Further, integration of data on proteome and transcriptome levels can validate gene signatures associated with a phenotype. Ho...

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Bibliographic Details
Main Authors: Tara Eicher, Andrew Patt, Esko Kautto, Raghu Machiraju, Ewy Mathé, Yan Zhang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3253-z