Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series

After tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after extraction can effectively reduce the resorption r...

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Main Authors: Hsi Kuei Lin, Yu Hwa Pan, Eisner Salamanca, Yu Te Lin, Wei Jen Chang
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:https://www.mdpi.com/1660-4601/16/23/4616
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spelling doaj-08c787e0ace1474e9e55ac45c1549f272020-11-24T21:50:05ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012019-11-011623461610.3390/ijerph16234616ijerph16234616Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case SeriesHsi Kuei Lin0Yu Hwa Pan1Eisner Salamanca2Yu Te Lin3Wei Jen Chang4School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110 TaiwanSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110 TaiwanSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110 TaiwanSunmax Biotech Co. Ltd., Tainan 744, TaiwanSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110 TaiwanAfter tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after extraction can effectively reduce the resorption rate of the alveolar ridge. The purpose of this study was to investigate the clinical efficacy of the application of a hydroxyapatite/&#946;-tricalcium plus collagen (HA/&#946;-TCP + collagen) dental bone graft in dental sockets immediately after tooth extraction, so as to prevent socket resorption. The study was conducted on 57 extraction sockets located in the mandible and maxilla posterior regions in 51 patients. HA/&#946;-TCP + collagen was inserted into all of the dental sockets immediately after extraction, and was covered with a flap. Follow-up was performed for three months after extraction, using radiographs and stents for the vertical and horizontal alveolar ridge measurements. A minimal alveolar bone width reduction of 1.03 &#177; 2.43 mm (<i>p</i> &lt; 0.05) was observed. The height reduction showed a slight decrease to 0.62 &#177; 1.46 mm (<i>p</i> &lt; 0.05). Radiographically, the bone height was maintained after three months, indicating a good HA/&#946;-TCP + collagen graft performance in preserving alveolar bone. In conclusion, the HA/&#946;-TCP + collagen graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction.https://www.mdpi.com/1660-4601/16/23/4616ha/β-tcp + collagen compositeperiodontal bone lossdental sockets preservationtooth extraction
collection DOAJ
language English
format Article
sources DOAJ
author Hsi Kuei Lin
Yu Hwa Pan
Eisner Salamanca
Yu Te Lin
Wei Jen Chang
spellingShingle Hsi Kuei Lin
Yu Hwa Pan
Eisner Salamanca
Yu Te Lin
Wei Jen Chang
Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
International Journal of Environmental Research and Public Health
ha/β-tcp + collagen composite
periodontal bone loss
dental sockets preservation
tooth extraction
author_facet Hsi Kuei Lin
Yu Hwa Pan
Eisner Salamanca
Yu Te Lin
Wei Jen Chang
author_sort Hsi Kuei Lin
title Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
title_short Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
title_full Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
title_fullStr Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
title_full_unstemmed Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series
title_sort prevention of bone resorption by ha/β-tcp + collagen composite after tooth extraction: a case series
publisher MDPI AG
series International Journal of Environmental Research and Public Health
issn 1660-4601
publishDate 2019-11-01
description After tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after extraction can effectively reduce the resorption rate of the alveolar ridge. The purpose of this study was to investigate the clinical efficacy of the application of a hydroxyapatite/&#946;-tricalcium plus collagen (HA/&#946;-TCP + collagen) dental bone graft in dental sockets immediately after tooth extraction, so as to prevent socket resorption. The study was conducted on 57 extraction sockets located in the mandible and maxilla posterior regions in 51 patients. HA/&#946;-TCP + collagen was inserted into all of the dental sockets immediately after extraction, and was covered with a flap. Follow-up was performed for three months after extraction, using radiographs and stents for the vertical and horizontal alveolar ridge measurements. A minimal alveolar bone width reduction of 1.03 &#177; 2.43 mm (<i>p</i> &lt; 0.05) was observed. The height reduction showed a slight decrease to 0.62 &#177; 1.46 mm (<i>p</i> &lt; 0.05). Radiographically, the bone height was maintained after three months, indicating a good HA/&#946;-TCP + collagen graft performance in preserving alveolar bone. In conclusion, the HA/&#946;-TCP + collagen graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction.
topic ha/β-tcp + collagen composite
periodontal bone loss
dental sockets preservation
tooth extraction
url https://www.mdpi.com/1660-4601/16/23/4616
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