Computational Analysis of Single Nucleotide Polymorphisms Associated with Altered Drug Responsiveness in Type 2 Diabetes

Computational Analysis of Single Nucleotide Polymorphisms Associated with Altered Drug Responsiveness in Type 2 Diabetes

Type 2 diabetes (T2D) is one of the most frequent mortality causes in western countries, with rapidly increasing prevalence. Anti-diabetic drugs are the first therapeutic approach, although many patients develop drug resistance. Most drug responsiveness variability can be explained by genetic causes...

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Bibliographic Details
Main Authors:	Valerio Costa, Antonio Federico, Carla Pollastro, Carmela Ziviello, Simona Cataldi, Pietro Formisano, Alfredo Ciccodicola
Format:	Article
Language:	English
Published:	MDPI AG 2016-06-01
Series:	International Journal of Molecular Sciences
Subjects:	type 2 diabetes drug responsiveness computational predictions pharmacogenomics personalized medicine RNA-sequencing
Online Access:	http://www.mdpi.com/1422-0067/17/7/1008

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