Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts
Gastric cancer is commonly treated by chemotherapy using 5-fluorouracil derivatives and platinum combination, but predictive biomarker remains lacking. Here, the authors develop a 30-gene prediction model to determine the responsiveness to 5-fluorouracil and oxaliplatin-based chemotherapy through th...
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Bibliographic Details
| Main Authors: |
Deukchae Na,
Jeesoo Chae,
Sung-Yup Cho,
Wonyoung Kang,
Ahra Lee,
Seoyeon Min,
Jinjoo Kang,
Min Jung Kim,
Jaeyong Choi,
Woochan Lee,
Dongjin Shin,
Ahrum Min,
Yu-Jin Kim,
Kyung-Hun Lee,
Tae-Yong Kim,
Yun-Suhk Suh,
Seong-Ho Kong,
Hyuk-Joon Lee,
Woo-Ho Kim,
Hansoo Park,
Seock-Ah Im,
Han-Kwang Yang,
Charles Lee,
Jong-Il Kim |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-25122-4
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