Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
Abstract Background The adaptive immune response intrinsically depends on hypervariable human leukocyte antigen (HLA) genes. Concomitantly, correct HLA phenotyping is crucial for successful donor-patient matching in organ transplantation. The cost and technical limitations of current laboratory tech...
Main Authors: | Maria Luisa Matey-Hernandez, Danish Pan Genome Consortium, Søren Brunak, Jose M. G. Izarzugaza |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-06-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2239-6 |
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