A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic B...

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Bibliographic Details
Main Authors: Yanjun Guo, Pamela M. Rist, Iyas Daghlas, Franco Giulianini, The International Headache Genetics Consortium, The 23andMe Research Team, Tobias Kurth, Daniel I. Chasman
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17002-0
Description
Summary:The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.
ISSN:2041-1723

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