Reconstructing metastatic seeding patterns of human cancers
Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases from next-generation sequencing data.
Main Authors: | Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Ivana Bozic, Krishnendu Chatterjee, Christine A. Iacobuzio-Donahue, Bert Vogelstein, Martin A. Nowak |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms14114 |
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