Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie.
Prion infectivity and its molecular marker, the pathological prion protein PrP(Sc), accumulate in the central nervous system and often also in lymphoid tissue of animals or humans affected by transmissible spongiform encephalopathies. Recently, PrP(Sc) was found in tissues previously considered not...
Main Authors: | Achim Thomzig, Walter Schulz-Schaeffer, Arne Wrede, Wilhelm Wemheuer, Bertram Brenig, Christine Kratzel, Karin Lemmer, Michael Beekes |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC1876502?pdf=render |
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