Fungicidal Drugs Induce a Common Oxidative-Damage Cellular Death Pathway

Amphotericin, miconazole, and ciclopirox are antifungal agents from three different drug classes that can effectively kill planktonic yeast, yet their complete fungicidal mechanisms are not fully understood. Here, we employ a systems biology approach to identify a common oxidative-damage cellular d...

Full description

Bibliographic Details
Main Authors: Peter Belenky, Diogo Camacho, James J. Collins
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000508