Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer

Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer

Bladder cancer (or urothelial cell carcinoma [UCC]) is characterized by field disease (malignant alterations in surrounding mucosa) and frequent recurrences. Whole-genome, exome, and transcriptome sequencing of 38 tumors, including four metachronous tumor pairs and 20 superficial tumors, identified...

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Main Authors: Iver Nordentoft, Philippe Lamy, Karin Birkenkamp-Demtröder, Karey Shumansky, Søren Vang, Henrik Hornshøj, Malene Juul, Palle Villesen, Jakob Hedegaard, Andrew Roth, Kasper Thorsen, Søren Høyer, Michael Borre, Thomas Reinert, Niels Fristrup, Lars Dyrskjøt, Sohrab Shah, Jakob Skou Pedersen, Torben F. Ørntoft
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714003404

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