A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps

A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps

<p>Abstract</p> <p>Background</p> <p>In the case of an autosomal locus, four transmission events from the parents to progeny are possible, specified by the grand parental origin of the alleles inherited by this individual. Computing the probabilities of these transmissi...

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Main Authors: Gilbert Hélène, Filangi Olivier, Elsen Jean-Michel, Le Roy Pascale, Moreno Carole
Format: Article
Language:deu
Published: BMC 2009-11-01
Series:Genetics Selection Evolution
Online Access:http://www.gsejournal.org/content/41/1/50
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spelling doaj-09728b1cf73a4f729eb704a1bbbd7e1d2020-11-24T21:19:07ZdeuBMCGenetics Selection Evolution0999-193X1297-96862009-11-014115010.1186/1297-9686-41-50A fast algorithm for estimating transmission probabilities in QTL detection designs with dense mapsGilbert HélèneFilangi OlivierElsen Jean-MichelLe Roy PascaleMoreno Carole<p>Abstract</p> <p>Background</p> <p>In the case of an autosomal locus, four transmission events from the parents to progeny are possible, specified by the grand parental origin of the alleles inherited by this individual. Computing the probabilities of these transmission events is essential to perform QTL detection methods.</p> <p>Results</p> <p>A fast algorithm for the estimation of these probabilities conditional to parental phases has been developed. It is adapted to classical QTL detection designs applied to outbred populations, in particular to designs composed of half and/or full sib families. It assumes the absence of interference.</p> <p>Conclusion</p> <p>The theory is fully developed and an example is given.</p> http://www.gsejournal.org/content/41/1/50
collection DOAJ
language deu
format Article
sources DOAJ
author Gilbert Hélène
Filangi Olivier
Elsen Jean-Michel
Le Roy Pascale
Moreno Carole
spellingShingle Gilbert Hélène
Filangi Olivier
Elsen Jean-Michel
Le Roy Pascale
Moreno Carole
A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
Genetics Selection Evolution
author_facet Gilbert Hélène
Filangi Olivier
Elsen Jean-Michel
Le Roy Pascale
Moreno Carole
author_sort Gilbert Hélène
title A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
title_short A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
title_full A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
title_fullStr A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
title_full_unstemmed A fast algorithm for estimating transmission probabilities in QTL detection designs with dense maps
title_sort fast algorithm for estimating transmission probabilities in qtl detection designs with dense maps
publisher BMC
series Genetics Selection Evolution
issn 0999-193X
1297-9686
publishDate 2009-11-01
description <p>Abstract</p> <p>Background</p> <p>In the case of an autosomal locus, four transmission events from the parents to progeny are possible, specified by the grand parental origin of the alleles inherited by this individual. Computing the probabilities of these transmission events is essential to perform QTL detection methods.</p> <p>Results</p> <p>A fast algorithm for the estimation of these probabilities conditional to parental phases has been developed. It is adapted to classical QTL detection designs applied to outbred populations, in particular to designs composed of half and/or full sib families. It assumes the absence of interference.</p> <p>Conclusion</p> <p>The theory is fully developed and an example is given.</p>
url http://www.gsejournal.org/content/41/1/50
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