Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells.
A crucial step in generating de novo immune responses is the polarization of naive cognate CD4+ T cells by pathogen-triggered dendritic cells (DC). In the human setting, standardized DC-dependent systems are lacking to study molecular events during the initiation of a naive CD4+ T cell response. We...
Main Authors: | Tammy Oth, Melanie C A Schnijderberg, Birgit L M G Senden-Gijsbers, Wilfred T V Germeraad, Gerard M J Bos, Joris Vanderlocht |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4140687?pdf=render |
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