Interaction of NMDA receptor and pacemaking mechanisms in the midbrain dopaminergic neuron.

Dopamine neurotransmission has been found to play a role in addictive behavior and is altered in psychiatric disorders. Dopaminergic (DA) neurons display two functionally distinct modes of electrophysiological activity: low- and high-frequency firing. A puzzling feature of the DA neuron is the follo...

Full description

Bibliographic Details
Main Authors: Joon Ha, Alexey Kuznetsov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3716766?pdf=render