A case series of concomitant burn and COVID-19
Background: The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease (COVID-19) has become a human pandemic. Heightened inflammation, vascular hyperpermeability, acute lung injury, coagulopathy, and cardiovascular abnormalities are among the SARS-CoV-2 infection-rela...
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doaj-09bd84d02fec48ad834e8e2835735b062020-12-21T04:47:59ZengElsevierBurns Open2468-91222021-01-01513438A case series of concomitant burn and COVID-19Mohammadhossein Hesamirostami0Roozbeh Nazarian1Hassan Asghari2Abdolreza Jafarirad3Ali Khosravi4Seyedehzahra Nouranibaladezaei5Azar Radfar6Department of Surgery, Plastic Surgery Division, Mazandaran University of Medical Sciences, Iran; Zare Hospital, Mazandaran University of Medical Sciences, IranIntegrated Medical Science Department, Florida Atlantic University – Charles E. Schmidt College of Medicine, USAZare Hospital, Mazandaran University of Medical Sciences, IranZare Hospital, Mazandaran University of Medical Sciences, IranZare Hospital, Mazandaran University of Medical Sciences, IranZare Hospital, Mazandaran University of Medical Sciences, IranDepartment of Medicine, Division of Cardiovascular Disease, University of Miami Miller School of Medicine, USA; Corresponding author: Department of Medicine, Division of Cardiovascular Disease University of Miami Miller School of Medicine 1600 NW 10th Ave #1140, Miami, FL 33136, USA.Background: The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease (COVID-19) has become a human pandemic. Heightened inflammation, vascular hyperpermeability, acute lung injury, coagulopathy, and cardiovascular abnormalities are among the SARS-CoV-2 infection-related complications. Major burn is also associated with metabolic derangements, vascular leak, and hemodynamic instability. Burn patients are at high risk for infections and developing sepsis. COVID-19 in burn victims might worsen the clinical outcome and make their medical management challenging. Result: Here, we present four cases of concomitant burn and COVID-19 with different degrees of complications. They had no (three out of four) or multiple (one out of four) baseline comorbidities and all were admitted to hospital for further management. Three out of four cases demonstrated acute respiratory failure and were intubated (no longer than 7 days). It seems that one of them had COVID-19 on arrival, the other apparently contracted at outside hospital, and the last two infected during the index hospitalization. Conclusion: Concomitant severe burn and COVID-19 might complicate the clinical presentation and hospital course. Such combination was associated with poor outcome in a case with baseline comorbidities, beyond what was expected from the severity of burn injury. However, a more comprehensive study with larger sample size is required to make a valid conclusion. With an ongoing COVID-19 global pandemic, SARS-CoV-2 infection might be a concurrent disease with other illnesses or traumas such as burn. This dictate multidisciplinary approaches to risk stratify, screen, assess, and manage coexisting diseases. Additionally, appropriate preparations and careful precautions need to be executed in burn units to prevent COVID-19 exposure and transmission to limit potential adverse outcomes.http://www.sciencedirect.com/science/article/pii/S2468912220300559BurnComorbidityCOVID-19SARS-CoV-2Acute respiratory failure |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammadhossein Hesamirostami Roozbeh Nazarian Hassan Asghari Abdolreza Jafarirad Ali Khosravi Seyedehzahra Nouranibaladezaei Azar Radfar |
spellingShingle |
Mohammadhossein Hesamirostami Roozbeh Nazarian Hassan Asghari Abdolreza Jafarirad Ali Khosravi Seyedehzahra Nouranibaladezaei Azar Radfar A case series of concomitant burn and COVID-19 Burns Open Burn Comorbidity COVID-19 SARS-CoV-2 Acute respiratory failure |
author_facet |
Mohammadhossein Hesamirostami Roozbeh Nazarian Hassan Asghari Abdolreza Jafarirad Ali Khosravi Seyedehzahra Nouranibaladezaei Azar Radfar |
author_sort |
Mohammadhossein Hesamirostami |
title |
A case series of concomitant burn and COVID-19 |
title_short |
A case series of concomitant burn and COVID-19 |
title_full |
A case series of concomitant burn and COVID-19 |
title_fullStr |
A case series of concomitant burn and COVID-19 |
title_full_unstemmed |
A case series of concomitant burn and COVID-19 |
title_sort |
case series of concomitant burn and covid-19 |
publisher |
Elsevier |
series |
Burns Open |
issn |
2468-9122 |
publishDate |
2021-01-01 |
description |
Background: The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease (COVID-19) has become a human pandemic. Heightened inflammation, vascular hyperpermeability, acute lung injury, coagulopathy, and cardiovascular abnormalities are among the SARS-CoV-2 infection-related complications. Major burn is also associated with metabolic derangements, vascular leak, and hemodynamic instability. Burn patients are at high risk for infections and developing sepsis. COVID-19 in burn victims might worsen the clinical outcome and make their medical management challenging. Result: Here, we present four cases of concomitant burn and COVID-19 with different degrees of complications. They had no (three out of four) or multiple (one out of four) baseline comorbidities and all were admitted to hospital for further management. Three out of four cases demonstrated acute respiratory failure and were intubated (no longer than 7 days). It seems that one of them had COVID-19 on arrival, the other apparently contracted at outside hospital, and the last two infected during the index hospitalization. Conclusion: Concomitant severe burn and COVID-19 might complicate the clinical presentation and hospital course. Such combination was associated with poor outcome in a case with baseline comorbidities, beyond what was expected from the severity of burn injury. However, a more comprehensive study with larger sample size is required to make a valid conclusion. With an ongoing COVID-19 global pandemic, SARS-CoV-2 infection might be a concurrent disease with other illnesses or traumas such as burn. This dictate multidisciplinary approaches to risk stratify, screen, assess, and manage coexisting diseases. Additionally, appropriate preparations and careful precautions need to be executed in burn units to prevent COVID-19 exposure and transmission to limit potential adverse outcomes. |
topic |
Burn Comorbidity COVID-19 SARS-CoV-2 Acute respiratory failure |
url |
http://www.sciencedirect.com/science/article/pii/S2468912220300559 |
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