Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b

Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b

Tolerogenic dendritic cells (toDCs) are crucial to controlling the development of autoreactive T cell responses and the prevention of autoimmunity. We have reported that NOD.CD11c<sup>Stat5b-CA</sup> transgenic mice expressing a constitutively active (CA) form of <i>Stat5b</i>...

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Bibliographic Details
Main Authors: Echarki Zerif, Farhan Ullah Khan, Ahmed Aziz Raki, Véronique Lullier, Denis Gris, Gilles Dupuis, Abdelaziz Amrani
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
tolerogenic dendritic cells
Interferon Regulatory Factor 4 and 8
Stat5b transcription factor
histone methyltransferase
nonobese diabetic mice
type 1 diabetes
Online Access:https://www.mdpi.com/1422-0067/21/18/6453

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https://www.mdpi.com/1422-0067/21/18/6453

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