Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARγ Dependent and Independent Mechanisms

Although thiazolidinediones (TZDs) were found to be ligands for peroxisome proliferators-activated receptorγ (PPARγ), the mechanism by which TZDs exert their anticancer effect remains unclear. Furthermore, the effect of TZDs on metastatic and angiogenesis potential of cancer cells is unknown. Our re...

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Bibliographic Details
Main Authors: Qing He, Ruiping Pang, Xin Song, Jie Chen, Huixin Chen, Baili Chen, Pinjin Hu, Minhu Chen
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/649808