Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions
Clostridium difficile is an anaerobic spore-forming human pathogen that is the leading cause of nosocomial infectious diarrhea worldwide. Germination of infectious spores is the first step in the development of a C. difficile infection (CDI) after ingestion and passage through the stomach. This stud...
Main Authors: | Travis J. Kochan, Michelle S. Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, Ashley D. Smith, Sally K. Zimmerman, Paul E. Carlson, Philip C. Hanna |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-09-01
|
Series: | mSphere |
Subjects: | |
Online Access: | https://doi.org/10.1128/mSphere.00335-18 |
Similar Items
-
Sensitizing Clostridium difficile Spores With Germinants on Skin and Environmental Surfaces Represents a New Strategy for Reducing Spores via Ambient Mechanisms
by: Michelle Marie Nerandzic, et al.
Published: (2017-10-01) -
Aerial dissemination of Clostridium difficile spores
by: Roberts, K., et al.
Published: (2008) -
Towards a Structural Understanding of Spore Germination in Clostridium Difficile
by: Adams, Chloe M.
Published: (2015) -
Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection
by: Duolong Zhu, et al.
Published: (2018-02-01) -
Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores.
by: Travis J Kochan, et al.
Published: (2017-07-01)