Xeno-Free Strategies for Safe Human Mesenchymal Stem/Stromal Cell Expansion: Supplements and Coatings

Xeno-Free Strategies for Safe Human Mesenchymal Stem/Stromal Cell Expansion: Supplements and Coatings

Human mesenchymal stem/stromal cells (hMSCs) have generated great interest in regenerative medicine mainly due to their multidifferentiation potential and immunomodulatory role. Although hMSC can be obtained from different tissues, the number of available cells is always low for clinical application...

Full description

Bibliographic Details
Main Authors:	M. Cimino, R. M. Gonçalves, C. C. Barrias, M. C. L. Martins
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2017/6597815

Similar Items

Synthetic surface for expansion of human mesenchymal stem cells in xeno-free, chemically defined culture conditions.
by: Paula J Dolley-Sonneville, et al.
Published: (2013-01-01)

Human Platelet lysate as a Xeno Free Alternative of Fetal bovine serum for the In Vitro Expansion of Human Mesenchymal Stromal Cells
by: Saeed Mohammadi, et al.
Published: (2016-06-01)

Human Bone Marrow Mesenchymal Stem/Stromal Cells Preserve Their Immunomodulatory and Chemotactic Properties When Expanded in a Human Plasma Derived Xeno-Free Medium
by: A. Blázquez-Prunera, et al.
Published: (2017-01-01)

Comparative Evaluation of Two Different Xeno‐Free Media Supplements in Umbilical Cord Tissue‐Derived Mesenchymal Stromal Cells In Vitro Culture
by: Ivan Chillik, et al.
Published: (2019-09-01)

Comparative evaluation of mesenchymal stromal cells from umbilical cord and amniotic membrane in xeno-free conditions
by: Yongxu Mu, et al.
Published: (2018-12-01)

Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate.
by: Ming-Li Chou, et al.
Published: (2014-01-01)

Easy xeno-free and feeder-free method for isolating and growing limbal stromal and epithelial stem cells of the human cornea.
by: Djida Ghoubay-Benallaoua, et al.
Published: (2017-01-01)

Comparative Bioactivity Analysis for Off-the-Shelf and Culture–Rescued Umbilical Cord-Derived Mesenchymal Stem/Stromal Cells in a Xeno- and Serum-Free Culture System
by: Minh Quang Nguyen, et al.
Published: (2021-09-01)

Effect of a good-manufacturing- practice xeno-free medium on mesenchymal stromal cell properties: Multipotentiality, immunomodulation and recruitment
by: Arantxa Blazquez Prunera
Published: (2020)

Xeno-Free Human Wharton’s Jelly Mesenchymal Stromal Cells Maintain Their Characteristic Properties after Long-Term Cryopreservation
by: Caroline Mathen, et al.
Published: (2021-07-01)

The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro
by: Maria Elisabetta Federica Palamà, et al.
Published: (2020-02-01)

Chemically Defined and Xeno-Free Cryopreservation of Human Adipose-Derived Stem Cells.
by: Melany López, et al.
Published: (2016-01-01)

Expansion of human mesenchymal stem/stromal cells on temporary liquid microcarriers
by: Coopman, K., et al.
Published: (2021)

Development of a Xeno-Free Feeder-Layer System from Human Umbilical Cord Mesenchymal Stem Cells for Prolonged Expansion of Human Induced Pluripotent Stem Cells in Culture.
by: Qing Zou, et al.
Published: (2016-01-01)

A synthetic, xeno-free peptide surface for expansion and directed differentiation of human induced pluripotent stem cells.
by: Sha Jin, et al.
Published: (2012-01-01)

GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells
by: Madison McGrath, et al.
Published: (2019-01-01)

Integrating xeno-free strategies with spheroid culture for stem-cell based therapies
by: Ewa Maria Bauman
Published: (2019)

Correction: A Synthetic, Xeno-Free Peptide Surface for Expansion and Directed Differentiation of Human Induced Pluripotent Stem Cells
by: Sha Jin, et al.
Published: (2013-01-01)

Correction: A Synthetic, Xeno-Free Peptide Surface for Expansion and Directed Differentiation of Human Induced Pluripotent Stem Cells.
by: Sha Jin, et al.
Published: (2013-01-01)

Xeno- and transgene-free reprogramming of mesenchymal stem cells toward the cells expressing neural markers using exosome treatments.
by: Luis Sebástian Alexis Valerio, et al.
Published: (2020-01-01)

Synthetic polymers as xeno-free materials for stabilizing basic fibroblast growth factor in human mesenchymal stem cell cultures
by: Yoko Masuzawa, et al.
Published: (2021-03-01)

Xeno-Free Propagation of Spermatogonial Stem Cells from Infant Boys
by: Lihua Dong, et al.
Published: (2019-10-01)

Improved GMP compliant approach to manipulate lipoaspirates, to cryopreserve stromal vascular fraction, and to expand adipose stem cells in xeno-free media
by: Francesco Agostini, et al.
Published: (2018-05-01)

Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems.
by: Sara M Badenes, et al.
Published: (2016-01-01)

Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System
by: Miguel de Almeida Fuzeta, et al.
Published: (2020-11-01)

Isolation, characterization, and gene expression analysis of Wharton&rsquo;s jelly-derived mesenchymal stem cells under xeno-free culture conditions
by: Venugopal P, et al.
Published: (2011-04-01)

Correction: Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems.
by: Sara M Badenes, et al.
Published: (2016-01-01)

Development of a Xeno-Free Substrate for Human Embryonic Stem Cell Growth
by: Hailin Zhu, et al.
Published: (2015-01-01)

Chemically defined and xeno-free culture condition for human extended pluripotent stem cells
by: Bei Liu, et al.
Published: (2021-05-01)

Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis
by: Souta Motoike, et al.
Published: (2019-08-01)

A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
by: Aliosha I. Figueroa-Valdés, et al.
Published: (2021-05-01)

Generation of Human-Induced Pluripotent Stem Cells by a Nonintegrating RNA Sendai Virus Vector in Feeder-Free or Xeno-Free Conditions
by: Chad C. MacArthur, et al.
Published: (2012-01-01)

Evaluation of a Xeno-Free Protocol for Long-Term Cryopreservation of Cord Blood Cells
by: M. Mairhofer, et al.
Published: (2013-06-01)

Induction of pluripotent stem cells by reprogramming human ocular fibroblasts under xeno-free conditions
by: Yunfan Xiong, et al.

Human mesenchymal stem cells maintain their phenotype, multipotentiality, and genetic stability when cultured using a defined xeno-free human plasma fraction
by: Arantxa Blázquez-Prunera, et al.
Published: (2017-04-01)

Mesenchymal Stromal Cell Immunology for Efficient and Safe Treatment of Osteoarthritis
by: Mehdi Najar, et al.
Published: (2020-09-01)

An Effective and Safe Supplement for Stem Cells Expansion Ex Vivo: Cord Blood Serum
by: Hai-Ying Ma, et al.
Published: (2012-05-01)

A Xeno-Free Strategy for Derivation of Human Umbilical Vein Endothelial Cells and Wharton’s Jelly Derived Mesenchymal Stromal Cells: A Feasibility Study toward Personal Cell and Vascular Based Therapy
by: Hataiwan Kunkanjanawan, et al.
Published: (2020-01-01)

Human Embryonic Stem Cells Culture on Growth Factor-immobilized Surface under Feeder-free and Xeno-free Conditions
by: Meng-Pei Li, et al.
Published: (2017)

Bioreactor Parameters for Microcarrier-Based Human MSC Expansion under Xeno-Free Conditions in a Vertical-Wheel System
by: Josephine Lembong, et al.
Published: (2020-07-01)