Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway.

Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway.

Inflammatory stress is an independent risk factor for the development of non-alcoholic fatty liver disease (NAFLD). Although CD36 is known to facilitate long-chain fatty acid uptake and contributes to NAFLD progression, the mechanisms that link inflammatory stress to hepatic CD36 expression and stea...

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Bibliographic Details
Main Authors: Chuan Wang, Lin Hu, Lei Zhao, Ping Yang, John F Moorhead, Zac Varghese, Yaxi Chen, Xiong Z Ruan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105654?pdf=render

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