Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide, with elevated intraocular pressure as an important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown...
Main Authors: | John Kuchtey, Lana M Olson, Tommy Rinkoski, Edward O Mackay, T M Iverson, Kirk N Gelatt, Jonathan L Haines, Rachel W Kuchtey |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3040645?pdf=render |
Similar Items
-
Worsening angle closure glaucoma and choroidal detachments subsequent to closure of a carotid cavernous fistula
by: Thinda Sumeer, et al.
Published: (2012-07-01) -
Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with ADAMTS10 Mutation.
by: Joel R Palko, et al.
Published: (2016-01-01) -
Not too long, not too short: Goldilocks principle of eye size.
by: Rachel W Kuchtey
Published: (2020-07-01) -
Differential effects of angiotensin II type I receptor blockers on reducing intraocular pressure and TGFβ signaling in the mouse retina.
by: Ralph J Hazlewood, et al.
Published: (2018-01-01) -
Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus.
by: Shakila Abdul-Majeed, et al.
Published: (2014-01-01)