Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon
Hematological abnormalities including thrombocytopenia are common in patients living with HIV infection. Patients with HIV infection related thrombocytopenia present generally with only minor bleeding problems. But cases of subdural hematoma are very rare. A 61-year-old female with a history of HIV...
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doaj-0a1dbcead78e489cac09fb967f8319672020-11-25T01:43:17ZengHindawi LimitedCase Reports in Neurological Medicine2090-66682090-66762017-01-01201710.1155/2017/53958295395829Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in CameroonClovis Nkoke0Engelbert Bain Luchuo1Denis Teuwafeu2Ines Nepetsoun3Cyrille Nkouonlack4Faculty of Medicine and Biomedical Sciences, University of Yaounde 1 and Buea Regional Hospital, Yaounde, CameroonCenter for Population Studies and Health Promotion, Yaounde, CameroonBuea Regional Hospital, Southwest Region, CameroonBuea Regional Hospital, Southwest Region, CameroonBuea Regional Hospital, Southwest Region, CameroonHematological abnormalities including thrombocytopenia are common in patients living with HIV infection. Patients with HIV infection related thrombocytopenia present generally with only minor bleeding problems. But cases of subdural hematoma are very rare. A 61-year-old female with a history of HIV infection of 9 years’ duration presented with a 3-month history of generalized headache associated with visual blurring and anterograde amnesia. There was no history of trauma or fever. She was treated empirically for cerebral toxoplasmosis for 6 weeks without any improvement of the symptoms. One week prior to admission, she developed weakness of the left side of the body. Clinical examination revealed left-sided hemiparesis. Computed tomography scan of the brain showed a 25 mm chronic right frontoparietotemporal subdural hematoma compressing the lateral ventricle with midline shift. There was no appreciable cerebral atrophy. A complete blood count showed leucopenia and thrombocytopenia at 92,000 cells/mm3. Her CD4-positive cell count was 48 cells/mm3 despite receiving combination antiretroviral therapy for 9 years. A complete blood count analysis suggestive of thrombocytopenia should raise suspicion of possibilities of noninfectious focal brain lesions like subdural hematoma amongst HIV infected patients presenting with nonspecific neurological symptoms. This will enable prompt diagnosis and allow early appropriate intervention.http://dx.doi.org/10.1155/2017/5395829 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Clovis Nkoke Engelbert Bain Luchuo Denis Teuwafeu Ines Nepetsoun Cyrille Nkouonlack |
spellingShingle |
Clovis Nkoke Engelbert Bain Luchuo Denis Teuwafeu Ines Nepetsoun Cyrille Nkouonlack Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon Case Reports in Neurological Medicine |
author_facet |
Clovis Nkoke Engelbert Bain Luchuo Denis Teuwafeu Ines Nepetsoun Cyrille Nkouonlack |
author_sort |
Clovis Nkoke |
title |
Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon |
title_short |
Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon |
title_full |
Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon |
title_fullStr |
Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon |
title_full_unstemmed |
Chronic Subdural Hematoma Associated with Thrombocytopenia in a Patient with Human Immunodeficiency Virus Infection in Cameroon |
title_sort |
chronic subdural hematoma associated with thrombocytopenia in a patient with human immunodeficiency virus infection in cameroon |
publisher |
Hindawi Limited |
series |
Case Reports in Neurological Medicine |
issn |
2090-6668 2090-6676 |
publishDate |
2017-01-01 |
description |
Hematological abnormalities including thrombocytopenia are common in patients living with HIV infection. Patients with HIV infection related thrombocytopenia present generally with only minor bleeding problems. But cases of subdural hematoma are very rare. A 61-year-old female with a history of HIV infection of 9 years’ duration presented with a 3-month history of generalized headache associated with visual blurring and anterograde amnesia. There was no history of trauma or fever. She was treated empirically for cerebral toxoplasmosis for 6 weeks without any improvement of the symptoms. One week prior to admission, she developed weakness of the left side of the body. Clinical examination revealed left-sided hemiparesis. Computed tomography scan of the brain showed a 25 mm chronic right frontoparietotemporal subdural hematoma compressing the lateral ventricle with midline shift. There was no appreciable cerebral atrophy. A complete blood count showed leucopenia and thrombocytopenia at 92,000 cells/mm3. Her CD4-positive cell count was 48 cells/mm3 despite receiving combination antiretroviral therapy for 9 years. A complete blood count analysis suggestive of thrombocytopenia should raise suspicion of possibilities of noninfectious focal brain lesions like subdural hematoma amongst HIV infected patients presenting with nonspecific neurological symptoms. This will enable prompt diagnosis and allow early appropriate intervention. |
url |
http://dx.doi.org/10.1155/2017/5395829 |
work_keys_str_mv |
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