Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment

Background: Infection with the hepatitis C virus (HCV) during pregnancy has emerged as an increasingly recognized and prevalent condition among women of reproductive age in the United States. While screening recommendations exist for pregnant women at high risk of HCV infection, pregnant women with...

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Main Authors: Preetha Nandi, Aley G. Kalapila, Martina L. Badell, Anandi N. Sheth
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Case Reports in Women's Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214911218300894
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spelling doaj-0a1ea637e3f54f60a7e50d5bc11d21fe2020-11-25T00:57:51ZengElsevierCase Reports in Women's Health2214-91122018-10-0120Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatmentPreetha Nandi0Aley G. Kalapila1Martina L. Badell2Anandi N. Sheth3Emory University School of Medicine, Atlanta, GA, United States; Corresponding author at: 100 Woodruff Circle, Atlanta, GA 30322, United States.Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, United StatesEmory University School of Medicine, Department of Gynecology and Obstetrics, Maternal-Fetal Medicine, Atlanta, GA, United StatesEmory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, United StatesBackground: Infection with the hepatitis C virus (HCV) during pregnancy has emerged as an increasingly recognized and prevalent condition among women of reproductive age in the United States. While screening recommendations exist for pregnant women at high risk of HCV infection, pregnant women with HCV are often under-screened, not diagnosed, or do not receive adequate follow-up, thereby increasing the risk of suboptimal maternal and infant outcomes (including in future pregnancies). Case: A pregnant woman living with HIV presented with intrahepatic cholestasis of pregnancy. She had tested negative for HCV earlier in pregnancy as part of routine screening recommended for women living with HIV. She was found to have sexually acquired a new HCV infection from her partner during pregnancy. She successfully completed treatment postpartum. Conclusion: With the rise in HCV infection among pregnant patients, physicians should be diligent in assessing pregnant women and their partners for HCV risk factors, testing for HCV when risk is identified, and arranging follow-up testing and treatment for HCV-positive mothers and their infants. Keywords: HCV, HCV in pregnancy, co-infection, HCV screening, high-risk obstetrics, HIVhttp://www.sciencedirect.com/science/article/pii/S2214911218300894
collection DOAJ
language English
format Article
sources DOAJ
author Preetha Nandi
Aley G. Kalapila
Martina L. Badell
Anandi N. Sheth
spellingShingle Preetha Nandi
Aley G. Kalapila
Martina L. Badell
Anandi N. Sheth
Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
Case Reports in Women's Health
author_facet Preetha Nandi
Aley G. Kalapila
Martina L. Badell
Anandi N. Sheth
author_sort Preetha Nandi
title Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
title_short Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
title_full Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
title_fullStr Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
title_full_unstemmed Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment
title_sort sexually acquired acute hepatitis c infection diagnosed during pregnancy: a case report of successful postpartum treatment
publisher Elsevier
series Case Reports in Women's Health
issn 2214-9112
publishDate 2018-10-01
description Background: Infection with the hepatitis C virus (HCV) during pregnancy has emerged as an increasingly recognized and prevalent condition among women of reproductive age in the United States. While screening recommendations exist for pregnant women at high risk of HCV infection, pregnant women with HCV are often under-screened, not diagnosed, or do not receive adequate follow-up, thereby increasing the risk of suboptimal maternal and infant outcomes (including in future pregnancies). Case: A pregnant woman living with HIV presented with intrahepatic cholestasis of pregnancy. She had tested negative for HCV earlier in pregnancy as part of routine screening recommended for women living with HIV. She was found to have sexually acquired a new HCV infection from her partner during pregnancy. She successfully completed treatment postpartum. Conclusion: With the rise in HCV infection among pregnant patients, physicians should be diligent in assessing pregnant women and their partners for HCV risk factors, testing for HCV when risk is identified, and arranging follow-up testing and treatment for HCV-positive mothers and their infants. Keywords: HCV, HCV in pregnancy, co-infection, HCV screening, high-risk obstetrics, HIV
url http://www.sciencedirect.com/science/article/pii/S2214911218300894
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