Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing

Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing

OBJECTIVE: To characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis (ABECB), with particular attention to the speed of bacterial killing. This was possible because the study design incorporated dai...

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Bibliographic Details
Main Author: Jerome J Schentag
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1998/407350
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spelling doaj-0a5113e2609445b39c77f0d82122f7f02020-11-24T23:59:39ZengHindawi LimitedCanadian Journal of Infectious Diseases1180-23321998-01-019Suppl E16E22E10.1155/1998/407350Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial KillingJerome J Schentag0SUNY, Buffalo Clinical Pharmacokinetics Laboratory, Millard Fillmore Health System, Buffalo, New York, USAOBJECTIVE: To characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis (ABECB), with particular attention to the speed of bacterial killing. This was possible because the study design incorporated daily cultures of the patients’ sputum.http://dx.doi.org/10.1155/1998/407350
collection DOAJ
language English
format Article
sources DOAJ
author Jerome J Schentag
spellingShingle Jerome J Schentag
Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
Canadian Journal of Infectious Diseases
author_facet Jerome J Schentag
author_sort Jerome J Schentag
title Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
title_short Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
title_full Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
title_fullStr Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
title_full_unstemmed Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing
title_sort grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis - a question of speed in bacterial killing
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases
issn 1180-2332
publishDate 1998-01-01
description OBJECTIVE: To characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis (ABECB), with particular attention to the speed of bacterial killing. This was possible because the study design incorporated daily cultures of the patients’ sputum.
url http://dx.doi.org/10.1155/1998/407350
work_keys_str_mv AT jeromejschentag grepafloxacininpatientswithacutebacterialexacerbationsofchronicbronchitisaquestionofspeedinbacterialkilling
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