Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils

Background: Bis-phenol A (BPA) can migrate into food stuff from packaging materials and accounts for food contamination. This research was designed to measure BPA contamination in the Iranian brands of food grade oils and to find out the possible effect of production date on the amount of BPA migrat...

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Main Authors: Mahboob Nemati, Sara Nofozi, Shirin Ahmadi, Farnaz Monajjemzadeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-141.pdf
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spelling doaj-0a5fee843aca4a05acfb2ab60e7bdd762021-03-02T09:51:13ZengTabriz University of Medical SciencesPharmaceutical Sciences1735-403X2383-28862018-06-0124214114710.15171/PS.2018.21PHARM_832_20170821114123Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade OilsMahboob Nemati0Sara Nofozi1Shirin Ahmadi2Farnaz Monajjemzadeh3Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Student Research Committee, Tabriz University of Medical sciences, Tabriz, Iran.Central lab, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Background: Bis-phenol A (BPA) can migrate into food stuff from packaging materials and accounts for food contamination. This research was designed to measure BPA contamination in the Iranian brands of food grade oils and to find out the possible effect of production date on the amount of BPA migration. Methods: Ten well-known and top selling oils packed in various containers, were selected and sampled according to their batch number and production date stated on the label. Subsequently, BPA was extracted by reverse phase dispersive liquid-liquid extraction (RP-DLLME) method and quantified by HPLC. Results: The measured quantity of BPA in the food grade oil was ranged between 0.5 to 4.37 µg/g of oil samples regardless of the date of production, the Batch Number, and the producing company. Statistical analysis revealed that the difference of BPA content in oil samples did not depend on their production date. Conclusion: According to the amount of allowable migration introduced by European committee, the amount of BPA migration and consequently contamination of almost all tested samples exceeds SML. Considering the toxic effects reported especially in fetus and young children, prompt regulatory interference is needed in this area.http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-141.pdfBisphenol AContaminationRP-DLLMEHPLCFood grade oilSampling Procedure
collection DOAJ
language English
format Article
sources DOAJ
author Mahboob Nemati
Sara Nofozi
Shirin Ahmadi
Farnaz Monajjemzadeh
spellingShingle Mahboob Nemati
Sara Nofozi
Shirin Ahmadi
Farnaz Monajjemzadeh
Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
Pharmaceutical Sciences
Bisphenol A
Contamination
RP-DLLME
HPLC
Food grade oil
Sampling Procedure
author_facet Mahboob Nemati
Sara Nofozi
Shirin Ahmadi
Farnaz Monajjemzadeh
author_sort Mahboob Nemati
title Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
title_short Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
title_full Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
title_fullStr Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
title_full_unstemmed Quality Control of the Migration of Bisphenol a from Plastic Packaging into Iranian Brands of Food Grade Oils
title_sort quality control of the migration of bisphenol a from plastic packaging into iranian brands of food grade oils
publisher Tabriz University of Medical Sciences
series Pharmaceutical Sciences
issn 1735-403X
2383-2886
publishDate 2018-06-01
description Background: Bis-phenol A (BPA) can migrate into food stuff from packaging materials and accounts for food contamination. This research was designed to measure BPA contamination in the Iranian brands of food grade oils and to find out the possible effect of production date on the amount of BPA migration. Methods: Ten well-known and top selling oils packed in various containers, were selected and sampled according to their batch number and production date stated on the label. Subsequently, BPA was extracted by reverse phase dispersive liquid-liquid extraction (RP-DLLME) method and quantified by HPLC. Results: The measured quantity of BPA in the food grade oil was ranged between 0.5 to 4.37 µg/g of oil samples regardless of the date of production, the Batch Number, and the producing company. Statistical analysis revealed that the difference of BPA content in oil samples did not depend on their production date. Conclusion: According to the amount of allowable migration introduced by European committee, the amount of BPA migration and consequently contamination of almost all tested samples exceeds SML. Considering the toxic effects reported especially in fetus and young children, prompt regulatory interference is needed in this area.
topic Bisphenol A
Contamination
RP-DLLME
HPLC
Food grade oil
Sampling Procedure
url http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-141.pdf
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