Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report
Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening immune disorder that may be either primary or secondary to infection, malignancy, or rheumatological disease. In tropical countries like India, secondary HLH is more commonly seen. Both Dengue fever and scrub typhus, which resu...
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Galenos Yayinevi
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doaj-0a614e9b940b4c9cb5f9edf2a881505e2021-05-07T14:51:23ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2021-12-0110110.4274/mjima.galenos.2021.2020.20Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case ReportH. C. Krishna KUMAR0https://orcid.org/0000-0003-1946-2232K. Jagadish KUMAR1https://orcid.org/0000-0001-9059-986XManjunath V. G2https://orcid.org/0000-0002-9059-1486Sangeetha BALAJI3https://orcid.org/0000-0002-6040-4483JSS Academy of Higher Education and Research, JSS Medical College, Department of Pediatrics, Mysore, IndiaJSS Academy of Higher Education and Research, JSS Medical College, Department of Pediatrics, Mysore, IndiaJSS Academy of Higher Education and Research, JSS Medical College, Department of Pediatrics, Mysore, IndiaJSS Academy of Higher Education and Research, JSS Medical College, Department of Pediatrics, Mysore, IndiaHemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening immune disorder that may be either primary or secondary to infection, malignancy, or rheumatological disease. In tropical countries like India, secondary HLH is more commonly seen. Both Dengue fever and scrub typhus, which result in more than half of all acute undifferentiated febrile illnesses in tropics, can occasionally result in HLH. Early diagnosis of HLH and institution of appropriate treatment can result in a good outcome. Although coinfections are common in tropical countries, HLH due to coinfections is rare. We are reporting a child diagnosed with HLH associated with coinfection with scrub typhus and Dengue fever that received early supportive treatment and recovered without needing chemotherapy.http://mjima.org/abstract.php?id=247hemophagocytic lymphohistiocytosisdengue infectionscrub typhuscoinfection |
collection |
DOAJ |
language |
Turkish |
format |
Article |
sources |
DOAJ |
author |
H. C. Krishna KUMAR K. Jagadish KUMAR Manjunath V. G Sangeetha BALAJI |
spellingShingle |
H. C. Krishna KUMAR K. Jagadish KUMAR Manjunath V. G Sangeetha BALAJI Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report Mediterranean Journal of Infection, Microbes and Antimicrobials hemophagocytic lymphohistiocytosis dengue infection scrub typhus coinfection |
author_facet |
H. C. Krishna KUMAR K. Jagadish KUMAR Manjunath V. G Sangeetha BALAJI |
author_sort |
H. C. Krishna KUMAR |
title |
Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report |
title_short |
Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report |
title_full |
Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report |
title_fullStr |
Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report |
title_full_unstemmed |
Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report |
title_sort |
hemophagocytic lymphohistiocytosis associated with coinfection of scrub typhus and dengue fever in a child: a case report |
publisher |
Galenos Yayinevi |
series |
Mediterranean Journal of Infection, Microbes and Antimicrobials |
issn |
2147-673X |
publishDate |
2021-12-01 |
description |
Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening immune disorder that may be either primary or secondary to infection, malignancy, or rheumatological disease. In tropical countries like India, secondary HLH is more commonly seen. Both Dengue fever and scrub typhus, which result in more than half of all acute undifferentiated febrile illnesses in tropics, can occasionally result in HLH. Early diagnosis of HLH and institution of appropriate treatment can result in a good outcome. Although coinfections are common in tropical countries, HLH due to coinfections is rare. We are reporting a child diagnosed with HLH associated with coinfection with scrub typhus and Dengue fever that received early supportive treatment and recovered without needing chemotherapy. |
topic |
hemophagocytic lymphohistiocytosis dengue infection scrub typhus coinfection |
url |
http://mjima.org/abstract.php?id=247 |
work_keys_str_mv |
AT hckrishnakumar hemophagocyticlymphohistiocytosisassociatedwithcoinfectionofscrubtyphusanddenguefeverinachildacasereport AT kjagadishkumar hemophagocyticlymphohistiocytosisassociatedwithcoinfectionofscrubtyphusanddenguefeverinachildacasereport AT manjunathvg hemophagocyticlymphohistiocytosisassociatedwithcoinfectionofscrubtyphusanddenguefeverinachildacasereport AT sangeethabalaji hemophagocyticlymphohistiocytosisassociatedwithcoinfectionofscrubtyphusanddenguefeverinachildacasereport |
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1721455325365665792 |