Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery is the Core

In neuronal cells, tau is a microtubule-associated protein placed in axons and alpha synuclein is enriched at presynaptic terminals. They display a propensity to form pathologic aggregates, which are considered the underlying cause of Alzheimer’s and Parkinson’s diseases. Their functional impairment...

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Bibliographic Details
Main Authors: Elena Vacchi, Alain Kaelin-Lang, Giorgia Melli
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
tau
Online Access:https://www.mdpi.com/1422-0067/21/14/5030