Antibodies against high frequency Gerbich 2 antigen (anti-Ge2): A real challenge in cross matching lab

Transfusion management of patients′ alloimmunized against high-prevalence erythrocyte antigens is often problematic in emergency situations. Gerbich (Ge) is very common blood group system and Gerbich-2 (Ge-2) antigen present in high frequency and outside Papua New Guinea population, Ge-2 negative po...

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Bibliographic Details
Main Author: Ravindra P Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=1;spage=88;epage=89;aulast=Singh
Description
Summary:Transfusion management of patients′ alloimmunized against high-prevalence erythrocyte antigens is often problematic in emergency situations. Gerbich (Ge) is very common blood group system and Gerbich-2 (Ge-2) antigen present in high frequency and outside Papua New Guinea population, Ge-2 negative population almost nil. To manage such kind of problems with real emergencies, implementation of rare donor registry program, cryopreservation of red cells of rare donors and biological cross matching to assess significance of these antibodies is warranted.
ISSN:0973-6247
1998-3565