Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments.

Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments.

Antivenoms, produced using animal hyperimmune plasma, remains the standard therapy for snakebites. Although effective against systemic damages, conventional antivenoms have limited efficacy against local tissue damage. Additionally, the hypersensitivity reactions, often elicited by antivenoms, the h...

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Main Authors: Nidiane D R Prado, Soraya S Pereira, Michele P da Silva, Michelle S S Morais, Anderson M Kayano, Leandro S Moreira-Dill, Marcos B Luiz, Fernando B Zanchi, André L Fuly, Maribel E F Huacca, Cleberson F Fernandes, Leonardo A Calderon, Juliana P Zuliani, Luiz H Pereira da Silva, Andreimar M Soares, Rodrigo G Stabeli, Carla F C Fernandes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4814101?pdf=render

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