Indirect oxidative stress from pulmonary inflammation exceeds direct oxidative stress from chemical damage to mitochondria
The term oxidative stress was introduced by the National Toxicology Program (NTP) in 1985. It is now invoked as a contributing mechanism to the induction of tumors in chronic rodent cancer bioassays following administration of a chemical agent, especially via inhalation. The term oxidative stress is...
Main Authors: | Carr J Smith, Thomas A Perfetti, Judy A King |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-04-01
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Series: | Toxicology Research and Application |
Online Access: | https://doi.org/10.1177/2397847319842845 |
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