Repurposing of α1-Adrenoceptor Antagonists: Impact in Renal Cancer

Repurposing of α1-Adrenoceptor Antagonists: Impact in Renal Cancer

Renal cancer ranks twelfth in incidence among cancers worldwide. Despite improving outcomes due to better therapeutic options and strategies, prognosis for those with metastatic disease remains poor. Current systemic therapeutic approaches include inhibiting pathways of angiogenesis, immune checkpoi...

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Bibliographic Details
Main Authors: Meredith Mihalopoulos, Zachary Dovey, Maddison Rose Archer, Talia G. Korn, Kennedy E. Okhawere, William Nkemdirim, Hassan Funchess, Ami Rambhia, Nihal Mohamed, Steven A. Kaplan, Reza Mehrazin, Dara Lundon, Che-Kai Tsao, Ketan K. Badani, Natasha Kyprianou
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
renal tumors
prevention
α1-adrenoceptor antagonists
anoikis
vascularity
Online Access:https://www.mdpi.com/2072-6694/12/9/2442

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