Lysosomal Fusion Dysfunction as a Unifying Hypothesis for Alzheimer's Disease Pathology

Lysosomal Fusion Dysfunction as a Unifying Hypothesis for Alzheimer's Disease Pathology

Alzheimer's disease is characterized pathologically by extracellular senile plaques, intracellular neurofibrillary tangles, and granulovacuolar degeneration. It has been debated whether these hallmark lesions are markers or mediators of disease progression, and numerous paradigms have been prop...

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Bibliographic Details
Main Authors:	Kristen E. Funk, Jeff Kuret
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	International Journal of Alzheimer's Disease
Online Access:	http://dx.doi.org/10.1155/2012/752894

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