The spatial biology of transcription and translation in rapidly growing Escherichia coli

The spatial biology of transcription and translation in rapidly growing Escherichia coli

Single-molecule fluorescence provides high resolution spatial distributions of ribosomes and RNA polymerase (RNAP) in live, rapidly growing E. coli. Ribosomes are more strongly segregated from the nucleoids (chromosomal DNA) than previous widefield fluorescence studies suggested. While most transcri...

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Bibliographic Details
Main Authors: Somenath eBakshi, Heejun eChoi, James Carl Weisshaar
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Microbiology
Subjects:
Ribosomes
E. coli
RNA polymerase
nucleoid structure
Single-molecule tracking live cell
DNA-ribosome spatial segregation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00636/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00636/full

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