Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils,...

Full description

Bibliographic Details
Main Authors: Dean D. Metcalfe, Ruby Pawankar, Steven J. Ackerman, Cem Akin, Frederic Clayton, Franco H. Falcone, Gerald J. Gleich, Anne-Marie Irani, Mats W. Johansson, Amy D. Klion, Kristin M. Leiferman, Francesca Levi-Schaffer, Gunnar Nilsson, Yoshimichi Okayama, Calman Prussin, John T. Schroeder, Lawrence B. Schwartz, Hans-Uwe Simon, Andrew F. Walls, Massimo Triggiani
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119301620
id doaj-0b04f9e8a917429cb8094f51e41d64e9
record_format Article
spelling doaj-0b04f9e8a917429cb8094f51e41d64e92020-11-25T01:27:47ZengElsevierWorld Allergy Organization Journal1939-45512016-01-019Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseasesDean D. Metcalfe0Ruby Pawankar1Steven J. Ackerman2Cem Akin3Frederic Clayton4Franco H. Falcone5Gerald J. Gleich6Anne-Marie Irani7Mats W. Johansson8Amy D. Klion9Kristin M. Leiferman10Francesca Levi-Schaffer11Gunnar Nilsson12Yoshimichi Okayama13Calman Prussin14John T. Schroeder15Lawrence B. Schwartz16Hans-Uwe Simon17Andrew F. Walls18Massimo Triggiani19Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA; Correspondence:Division of Allergy, Department of Pediatrics, Nippon Medical School, Tokyo, JapanDepartment of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois, Chicago, IL, USAHarvard Medical School, Brigham and Women’s Hospital, Boston, MA, USADepartment of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USAThe School of Pharmacy, University of Nottingham, Nottingham, United KingdomDepartment of Dermatology, University of Utah, School of Medicine, Salt Lake City, UT, USAVirginia Commonwealth University, Children’s Hospital of Richmond, Richmond, VA, USADepartment of Biomolecular Chemistry, University of Wisconsin, Madison, WI, USAHuman Eosinophil Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USAUniversity of Utah, Salt Lake City, UT, USAThe Hebrew University of Jerusalem, Jerusalem, IsraelClinical Immunology and Allergy, Department of Medicine, Karolinska Institute and Karolinska University Hospital, Stockholm, SwedenAllergy and Immunology Group, Research Institute of Medical Science, Nihon University Graduate School of Medicine, Tokyo, JapanLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USADivision of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USAVirginia Commonwealth University, Richmond, VA, USAUniversity of Bern, Institute of Pharmacology, Bern, SwitzerlandSouthampton General Hospital, Immunopharmacology Group, Southampton, Hampshire, UKDivision of Allergy and Clinical Immunology, University of Salerno, Salerno, ItalyBiomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology.http://www.sciencedirect.com/science/article/pii/S1939455119301620
collection DOAJ
language English
format Article
sources DOAJ
author Dean D. Metcalfe
Ruby Pawankar
Steven J. Ackerman
Cem Akin
Frederic Clayton
Franco H. Falcone
Gerald J. Gleich
Anne-Marie Irani
Mats W. Johansson
Amy D. Klion
Kristin M. Leiferman
Francesca Levi-Schaffer
Gunnar Nilsson
Yoshimichi Okayama
Calman Prussin
John T. Schroeder
Lawrence B. Schwartz
Hans-Uwe Simon
Andrew F. Walls
Massimo Triggiani
spellingShingle Dean D. Metcalfe
Ruby Pawankar
Steven J. Ackerman
Cem Akin
Frederic Clayton
Franco H. Falcone
Gerald J. Gleich
Anne-Marie Irani
Mats W. Johansson
Amy D. Klion
Kristin M. Leiferman
Francesca Levi-Schaffer
Gunnar Nilsson
Yoshimichi Okayama
Calman Prussin
John T. Schroeder
Lawrence B. Schwartz
Hans-Uwe Simon
Andrew F. Walls
Massimo Triggiani
Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
World Allergy Organization Journal
author_facet Dean D. Metcalfe
Ruby Pawankar
Steven J. Ackerman
Cem Akin
Frederic Clayton
Franco H. Falcone
Gerald J. Gleich
Anne-Marie Irani
Mats W. Johansson
Amy D. Klion
Kristin M. Leiferman
Francesca Levi-Schaffer
Gunnar Nilsson
Yoshimichi Okayama
Calman Prussin
John T. Schroeder
Lawrence B. Schwartz
Hans-Uwe Simon
Andrew F. Walls
Massimo Triggiani
author_sort Dean D. Metcalfe
title Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
title_short Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
title_full Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
title_fullStr Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
title_full_unstemmed Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
title_sort biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
publisher Elsevier
series World Allergy Organization Journal
issn 1939-4551
publishDate 2016-01-01
description Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology.
url http://www.sciencedirect.com/science/article/pii/S1939455119301620
work_keys_str_mv AT deandmetcalfe biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT rubypawankar biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT stevenjackerman biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT cemakin biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT fredericclayton biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT francohfalcone biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT geraldjgleich biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT annemarieirani biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT matswjohansson biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT amydklion biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT kristinmleiferman biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT francescalevischaffer biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT gunnarnilsson biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT yoshimichiokayama biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT calmanprussin biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT johntschroeder biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT lawrencebschwartz biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT hansuwesimon biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT andrewfwalls biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
AT massimotriggiani biomarkersoftheinvolvementofmastcellsbasophilsandeosinophilsinasthmaandallergicdiseases
_version_ 1725103325508009984

Similar Items