Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy
Non Steroidal Anti Inflammatory Drugs (NSAID) have been associated with a sudden and sustained rise in the incidence of gastrointestinal ulcer complications. The aim of the study was to reveal the endoscopical abnormalities found in the duodenum & proximal jejunum due to NSAID. Thirty eight pat...
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Faculty of Medicine Universitas Indonesia
2005-11-01
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doaj-0b1195b243c747019257ac5c6584085e2020-11-25T01:30:12ZengFaculty of Medicine Universitas Indonesia Medical Journal of Indonesia0853-17732252-80832005-11-0114410.13181/mji.v14i4.200200Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathyMarcellus SimadibrataG. N.J. TytgatL. A. LesmanDaldiyono DaldiyonoIwan Ariawan Non Steroidal Anti Inflammatory Drugs (NSAID) have been associated with a sudden and sustained rise in the incidence of gastrointestinal ulcer complications. The aim of the study was to reveal the endoscopical abnormalities found in the duodenum & proximal jejunum due to NSAID. Thirty eight patients taking NSAID for their arthritis or rheumatism were included in this study. Gastro-duodeno-jejunoscopy was done with Olympus PCF-10. The endoscopical appearances of NSAID entero gastropathy were evaluated with a scoring system. The NSAID-entero-gastropathy appearances were endoscopically seen as hyperemia, erosion and ulcer. From all patient recruited, 7.9% complaint of diarrhea and 71.1% complaint of dyspepsia. Endoscopically, in the duodenal bulb we found 79% cases of hyperemia, 39.5% cases of erosion and 7.9% cases of ulcer. In the second part (descending part) of the duodenum we found 28.9% cases of hyperemia, 15.8% cases of erosion and 2.6% case of ulcer. In the jejunum, we found 7.9% cases of hyperemia, 2.6% case of erosion and no ulcer. It is concluded that the most frequent abnormal endoscopical appearances in NSAID- enteropathy was hyperemia. The most frequent site of NSAID-enteropathy abnormal findings was in the duodenal bulb. (Med J Indones 2005; 14: 225-9) Keywords: NSAID-enteropathy, endoscopical appearances. http://mji.ui.ac.id/journal/index.php/mji/article/view/200 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marcellus Simadibrata G. N.J. Tytgat L. A. Lesman Daldiyono Daldiyono Iwan Ariawan |
spellingShingle |
Marcellus Simadibrata G. N.J. Tytgat L. A. Lesman Daldiyono Daldiyono Iwan Ariawan Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy Medical Journal of Indonesia |
author_facet |
Marcellus Simadibrata G. N.J. Tytgat L. A. Lesman Daldiyono Daldiyono Iwan Ariawan |
author_sort |
Marcellus Simadibrata |
title |
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy |
title_short |
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy |
title_full |
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy |
title_fullStr |
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy |
title_full_unstemmed |
Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy |
title_sort |
endoscopical appearances of nonsteroidal anti inflammatory drug (nsaid)- enteropathy |
publisher |
Faculty of Medicine Universitas Indonesia |
series |
Medical Journal of Indonesia |
issn |
0853-1773 2252-8083 |
publishDate |
2005-11-01 |
description |
Non Steroidal Anti Inflammatory Drugs (NSAID) have been associated with a sudden and sustained rise in the incidence of gastrointestinal ulcer complications. The aim of the study was to reveal the endoscopical abnormalities found in the duodenum & proximal jejunum due to NSAID. Thirty eight patients taking NSAID for their arthritis or rheumatism were included in this study. Gastro-duodeno-jejunoscopy was done with Olympus PCF-10. The endoscopical appearances of NSAID entero gastropathy were evaluated with a scoring system. The NSAID-entero-gastropathy appearances were endoscopically seen as hyperemia, erosion and ulcer. From all patient recruited, 7.9% complaint of diarrhea and 71.1% complaint of dyspepsia. Endoscopically, in the duodenal bulb we found 79% cases of hyperemia, 39.5% cases of erosion and 7.9% cases of ulcer. In the second part (descending part) of the duodenum we found 28.9% cases of hyperemia, 15.8% cases of erosion and 2.6% case of ulcer. In the jejunum, we found 7.9% cases of hyperemia, 2.6% case of erosion and no ulcer. It is concluded that the most frequent abnormal endoscopical appearances in NSAID- enteropathy was hyperemia. The most frequent site of NSAID-enteropathy abnormal findings was in the duodenal bulb. (Med J Indones 2005; 14: 225-9)
Keywords: NSAID-enteropathy, endoscopical appearances.
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url |
http://mji.ui.ac.id/journal/index.php/mji/article/view/200 |
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