The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons.
Biallelic mutations in DONSON, an essential gene encoding for a replication fork protection factor, were linked to skeletal abnormalities and microcephaly. To better understand DONSON function in corticogenesis, we characterized Donson expression and consequences of conditional Donson deletion in th...
Main Authors: | Sathish Venkataramanappa, Dagmar Schütz, Friederike Saaber, Praveen Ashok Kumar, Philipp Abe, Stefan Schulz, Ralf Stumm |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-03-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009441 |
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