Micro RNAs upregulated in Vitiligo skin play an important role in its aetiopathogenesis by altering TRP1 expression and keratinocyte-melanocytes cross-talk
Abstract Translation of genes is regulated by many factors including microRNAs (miRNAs). miRNA profiling of lesional and non-lesional epidermal RNA from 18 vitiligo patients revealed significant upregulation of 29 miRNAs in the lesional epidermis, of which 6 miRNAs were transfected in normal human e...
Main Authors: | Utpreksha Vaish, Avinash A. Kumar, Swati Varshney, Shreya Ghosh, Shantanu Sengupta, Chandni Sood, Hemanta K. Kar, Pankaj Sharma, Vivek T. Natarajan, Rajesh S. Gokhale, Rajni Rani |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-46529-6 |
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