Rituximab combination therapy in relapsing multiple sclerosis

In multiple sclerosis (MS), the presence of B cells, plasma cells and excess immunoglobulins in central nervous system lesions and in the cerebrospinal fluid implicate the humoral immune system in disease pathogenesis. However, until the advent of specific B-cell-depleting therapies, the critical ro...

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Bibliographic Details
Main Authors: Anne H. Cross, Robyn S. Klein, Laura Piccio
Format: Article
Language:English
Published: SAGE Publishing 2012-11-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285612461165